Flights from United States to Panama from $ 348*

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Best prices for United flights from United States to Panama

$
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  • Austin (AUS)to

    Panama City (PTY)
    04/27/26 - 05/11/26
    from
    $ 538
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    04/07/26 - 04/21/26
    from
    $ 461
    Viewed: 10 hours ago
    Roundtrip
    Economy

    Los Angeles (LAX)to

    Panama City (PTY)
    04/27/26 - 05/01/26
    from
    $ 694
    Viewed: 12 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    04/29/26 - 05/06/26
    from
    $ 1,265
    Viewed: 12 hours ago
    Roundtrip
    Economy

  • Chicago (ORD)to

    Panama City (PTY)
    04/28/26 - 05/12/26
    from
    $ 738
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Washington, D.C. (IAD)to

    Panama City (PTY)
    04/28/26 - 05/12/26
    from
    $ 549
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Las Vegas (LAS)to

    Panama City (PTY)
    04/27/26 - 05/04/26
    from
    $ 706
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Boston (BOS)to

    Panama City (PTY)
    04/28/26 - 05/02/26
    from
    $ 697
    Viewed: 14 hours ago
    Roundtrip
    Economy

  • San Diego (SAN)to

    Panama City (PTY)
    04/27/26 - 05/04/26
    from
    $ 737
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Dallas (DFW)to

    Panama City (PTY)
    04/28/26 - 05/05/26
    from
    $ 1,215
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Fort Lauderdale (FLL)to

    Panama City (PTY)
    03/31/26 - 04/04/26
    from
    $ 348
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Cleveland (CLE)to

    Panama City (PTY)
    04/27/26 - 05/04/26
    from
    $ 631
    Viewed: 14 hours ago
    Roundtrip
    Economy

  • Indianapolis (IND)to

    Panama City (PTY)
    04/02/26 - 04/16/26
    from
    $ 517
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Oklahoma City (OKC)to

    Panama City (PTY)
    04/28/26 - 05/05/26
    from
    $ 663
    Viewed: 4 hours ago
    Roundtrip
    Economy

    Sacramento (SMF)to

    Panama City (PTY)
    04/28/26 - 05/05/26
    from
    $ 765
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Tucson (TUS)to

    Panama City (PTY)
    04/29/26 - 05/13/26
    from
    $ 695
    Viewed: 11 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
05/23/26 - 05/30/26

Roundtrip

Business

from
$ 1,375
Viewed: 1 day ago

Houston (IAH)to

Panama City (PTY)
04/05/26 - 04/09/26

Roundtrip

Business

from
$ 1,443
Viewed: 3 hours ago

San Francisco (SFO)to

Panama City (PTY)
05/14/26 - 05/18/26

Roundtrip

Business

from
$ 1,514
Viewed: 1 day ago

Denver (DEN)to

Panama City (PTY)
06/10/26 - 06/16/26

Roundtrip

Business

from
$ 1,022
Viewed: 10 hours ago

Seattle (SEA)to

Panama City (PTY)
01/04/27 - 02/18/27

Roundtrip

Business

from
$ 3,595
Viewed: 3 hours ago

Phoenix (PHX)to

Panama City (PTY)
05/04/26 - 05/11/26

Roundtrip

Business

from
$ 1,505
Viewed: 1 day ago

Washington, D.C. (IAD)to

Panama City (PTY)
05/30/26 - 06/05/26

Roundtrip

Business

from
$ 1,042
Viewed: 14 minutes ago

Chicago (ORD)to

Panama City (PTY)
08/01/26 - 08/03/26

Roundtrip

Business

from
$ 1,042
Viewed: 4 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama