Flights from United States to Panama from $ 394*

Promotion Code

Changed bag rules and optional services         Cruise Packages

Best prices for United flights from United States to Panama

$
keyboard_arrow_down

  • Los Angeles (LAX)to

    Panama City (PTY)
    12/16/25 - 12/21/25
    from
    $ 788
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Denver (DEN)to

    Panama City (PTY)
    12/19/25 - 12/25/25
    from
    $ 678
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Chicago (ORD)to

    Panama City (PTY)
    12/23/25 - 12/27/25
    from
    $ 1,027
    Viewed: 10 hours ago
    Roundtrip
    Economy

    San Antonio (SAT)to

    Panama City (PTY)
    12/30/25 - 02/17/26
    from
    $ 540
    Viewed: 14 hours ago
    Roundtrip
    Economy

  • Indianapolis (IND)to

    Panama City (PTY)
    12/16/25 - 01/06/26
    from
    $ 991
    Viewed: 17 hours ago
    Roundtrip
    Economy

    San Diego (SAN)to

    Panama City (PTY)
    12/16/25 - 12/21/25
    from
    $ 472
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    12/30/25 - 02/17/26
    from
    $ 489
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    12/16/25 - 12/23/25
    from
    $ 730
    Viewed: 12 hours ago
    Roundtrip
    Economy

  • Washington, D.C. (IAD)to

    Panama City (PTY)
    12/28/25 - 01/01/26
    from
    $ 1,287
    Viewed: 5 minutes ago
    Roundtrip
    Economy

    New Orleans (MSY)to

    Panama City (PTY)
    12/28/25 - 01/01/26
    from
    $ 509
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    12/17/25 - 12/21/25
    from
    $ 618
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Portland, OR (PDX)to

    Panama City (PTY)
    12/30/25 - 01/14/26
    from
    $ 743
    Viewed: 14 hours ago
    Roundtrip
    Economy

  • Pensacola (PNS)to

    Panama City (PTY)
    01/01/26 - 01/15/26
    from
    $ 497
    Viewed: 12 hours ago
    Roundtrip
    Economy

    Saint Louis (STL)to

    Panama City (PTY)
    12/09/25 - 12/22/25
    from
    $ 591
    Viewed: 1 hour ago
    Roundtrip
    Economy

    Tampa (TPA)to

    Panama City (PTY)
    01/01/26 - 01/05/26
    from
    $ 940
    Viewed: 3 hours ago
    Roundtrip
    Economy

    Atlanta (ATL)to

    Panama City (PTY)
    12/15/25 - 01/08/26
    from
    $ 856
    Viewed: 14 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
03/02/26 - 03/09/26

Roundtrip

Business

from
$ 1,278
Viewed: 15 hours ago

Houston (IAH)to

Panama City (PTY)
12/28/25 - 01/01/26

Roundtrip

Business

from
$ 1,371
Viewed: 13 hours ago

San Francisco (SFO)to

Panama City (PTY)
05/24/26 - 05/29/26

Roundtrip

Business

from
$ 1,374
Viewed: 11 hours ago

Denver (DEN)to

Panama City (PTY)
12/07/25 - 12/12/25

Roundtrip

Business

from
$ 1,134
Viewed: 14 hours ago

Dallas (DFW)to

Panama City (PTY)
12/07/25 - 12/13/25

Roundtrip

Business

from
$ 1,110
Viewed: 1 hour ago

Los Angeles (LAX)to

Panama City (PTY)
12/23/25 - 01/14/26

Roundtrip

Business

from
$ 1,477
Viewed: 5 hours ago

Chicago (ORD)to

Panama City (PTY)
01/27/26 - 01/29/26

Roundtrip

Business

from
$ 937
Viewed: 1 hour ago

San Antonio (SAT)to

Panama City (PTY)
12/30/25 - 02/17/26

Roundtrip

Business

from
$ 1,046
Viewed: 14 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama