Flights from United States to Panama from $ 385*

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Best prices for United flights from United States to Panama

$
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  • Denver (DEN)to

    Panama City (PTY)
    02/23/26 - 03/09/26
    from
    $ 630
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    02/23/26 - 02/27/26
    from
    $ 524
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Washington, D.C. (IAD)to

    Panama City (PTY)
    02/24/26 - 03/10/26
    from
    $ 563
    Viewed: 15 hours ago
    Roundtrip
    Economy

    Chicago (ORD)to

    Panama City (PTY)
    02/21/26 - 02/28/26
    from
    $ 682
    Viewed: 14 hours ago
    Roundtrip
    Economy

  • Los Angeles (LAX)to

    Panama City (PTY)
    02/23/26 - 03/02/26
    from
    $ 715
    Viewed: 15 hours ago
    Roundtrip
    Economy

    San Diego (SAN)to

    Panama City (PTY)
    02/23/26 - 02/27/26
    from
    $ 615
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    02/24/26 - 03/03/26
    from
    $ 657
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Sacramento (SMF)to

    Panama City (PTY)
    02/23/26 - 03/02/26
    from
    $ 711
    Viewed: 13 hours ago
    Roundtrip
    Economy

  • Atlanta (ATL)to

    Panama City (PTY)
    02/23/26 - 03/09/26
    from
    $ 385
    Viewed: 17 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    02/23/26 - 03/09/26
    from
    $ 681
    Viewed: 13 hours ago
    Roundtrip
    Economy

    Fort Lauderdale (FLL)to

    Panama City (PTY)
    02/23/26 - 03/09/26
    from
    $ 445
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    02/23/26 - 02/27/26
    from
    $ 445
    Viewed: 15 hours ago
    Roundtrip
    Economy

  • Portland, OR (PDX)to

    Panama City (PTY)
    02/24/26 - 03/10/26
    from
    $ 721
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Louisville (SDF)to

    Panama City (PTY)
    01/27/26 - 02/10/26
    from
    $ 445
    Viewed: 7 hours ago
    Roundtrip
    Economy

    New Orleans (MSY)to

    Panama City (PTY)
    02/24/26 - 03/10/26
    from
    $ 413
    Viewed: 14 hours ago
    Roundtrip
    Economy

    San Antonio (SAT)to

    Panama City (PTY)
    02/24/26 - 03/10/26
    from
    $ 561
    Viewed: 13 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
12/06/26 - 12/13/26

Roundtrip

Business

from
$ 1,342
Viewed: 10 hours ago

Houston (IAH)to

Panama City (PTY)
02/26/26 - 03/05/26

Roundtrip

Business

from
$ 1,578
Viewed: 16 hours ago

San Francisco (SFO)to

Panama City (PTY)
04/07/26 - 04/14/26

Roundtrip

Business

from
$ 1,585
Viewed: 5 hours ago

Dallas (DFW)to

Panama City (PTY)
05/25/26 - 05/31/26

Roundtrip

Business

from
$ 891
Viewed: 15 hours ago

Denver (DEN)to

Panama City (PTY)
03/17/26 - 05/15/26

Roundtrip

Business

from
$ 1,158
Viewed: 8 hours ago

Austin (AUS)to

Panama City (PTY)
02/01/26 - 02/05/26

Roundtrip

Business

from
$ 995
Viewed: 12 hours ago

Washington, D.C. (IAD)to

Panama City (PTY)
03/09/26 - 03/13/26

Roundtrip

Business

from
$ 1,151
Viewed: 16 hours ago

Chicago (ORD)to

Panama City (PTY)
03/27/26 - 03/29/26

Roundtrip

Business

from
$ 1,189
Viewed: 16 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama