Flights from the United States to Panama from $ 417*

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Best prices for United flights from United States to Panama

$
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  • Los Angeles (LAX)to

    Panama City (PTY)
    06/16/26 - 07/26/26
    from
    $ 771
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Chicago (ORD)to

    Panama City (PTY)
    06/21/26 - 06/25/26
    from
    $ 788
    Viewed: 6 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    06/17/26 - 06/24/26
    from
    $ 809
    Viewed: 23 hours ago
    Roundtrip
    Economy

    Washington, D.C. (IAD)to

    Panama City (PTY)
    06/21/26 - 06/26/26
    from
    $ 672
    Viewed: 22 hours ago
    Roundtrip
    Economy

  • Denver (DEN)to

    Panama City (PTY)
    06/21/26 - 06/25/26
    from
    $ 703
    Viewed: 8 hours ago
    Roundtrip
    Economy

    Indianapolis (IND)to

    Panama City (PTY)
    06/04/26 - 06/08/26
    from
    $ 567
    Viewed: 8 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    06/03/26 - 06/17/26
    from
    $ 551
    Viewed: 7 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    06/04/26 - 06/11/26
    from
    $ 511
    Viewed: 6 hours ago
    Roundtrip
    Economy

  • Raleigh (RDU)to

    Panama City (PTY)
    06/16/26 - 06/23/26
    from
    $ 613
    Viewed: 36 minutes ago
    Roundtrip
    Economy

    Orlando (MCO)to

    Panama City (PTY)
    06/22/26 - 06/29/26
    from
    $ 663
    Viewed: 7 hours ago
    Roundtrip
    Economy

    Charlotte (CLT)to

    Panama City (PTY)
    05/27/26 - 06/10/26
    from
    $ 589
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    06/20/26 - 06/24/26
    from
    $ 618
    Viewed: 10 hours ago
    Roundtrip
    Economy

  • Saint Louis (STL)to

    Panama City (PTY)
    06/22/26 - 06/29/26
    from
    $ 555
    Viewed: 5 hours ago
    Roundtrip
    Economy

    San Diego (SAN)to

    Panama City (PTY)
    06/20/26 - 06/24/26
    from
    $ 777
    Viewed: 6 hours ago
    Roundtrip
    Economy

    Boston (BOS)to

    Panama City (PTY)
    06/22/26 - 06/29/26
    from
    $ 747
    Viewed: 9 hours ago
    Roundtrip
    Economy

    Fort Lauderdale (FLL)to

    Panama City (PTY)
    06/09/26 - 06/16/26
    from
    $ 503
    Viewed: 8 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
08/31/26 - 12/10/26

Roundtrip

Business

from
$ 1,474
Viewed: 23 hours ago

Houston (IAH)to

Panama City (PTY)
07/01/26 - 07/08/26

Roundtrip

Business

from
$ 1,582
Viewed: 21 hours ago

Dallas (DFW)to

Panama City (PTY)
08/01/26 - 08/05/26

Roundtrip

Business

from
$ 958
Viewed: 1 day ago

San Francisco (SFO)to

Panama City (PTY)
07/31/26 - 08/07/26

Roundtrip

Business

from
$ 1,569
Viewed: 22 hours ago

Los Angeles (LAX)to

Panama City (PTY)
06/16/26 - 07/26/26

Roundtrip

Business

from
$ 1,185
Viewed: 2 hours ago

Chicago (ORD)to

Panama City (PTY)
08/09/26 - 08/13/26

Roundtrip

Business

from
$ 1,167
Viewed: 1 day ago

Miami (MIA)to

Panama City (PTY)
07/02/26 - 07/05/26

Roundtrip

Business

from
$ 1,467
Viewed: 18 hours ago

Indianapolis (IND)to

Panama City (PTY)
07/27/26 - 08/02/26

Roundtrip

Business

from
$ 987
Viewed: 23 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from the United States to Panama