Flights from United States to Panama from $ 327*

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Best prices for United flights from United States to Panama

$
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  • Los Angeles (LAX)to

    Panama City (PTY)
    03/16/26 - 03/20/26
    from
    $ 614
    Viewed: 3 hours ago
    Roundtrip
    Economy

    San Antonio (SAT)to

    Panama City (PTY)
    03/17/26 - 03/31/26
    from
    $ 571
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Washington, D.C. (IAD)to

    Panama City (PTY)
    03/17/26 - 03/19/26
    from
    $ 489
    Viewed: 1 day ago
    Roundtrip
    Economy

    Chicago (ORD)to

    Panama City (PTY)
    03/17/26 - 03/24/26
    from
    $ 653
    Viewed: 2 hours ago
    Roundtrip
    Economy

  • Portland, OR (PDX)to

    Panama City (PTY)
    03/03/26 - 03/17/26
    from
    $ 421
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Dallas (DFW)to

    Panama City (PTY)
    03/09/26 - 03/18/26
    from
    $ 1,122
    Viewed: 5 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    03/03/26 - 03/07/26
    from
    $ 759
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    03/17/26 - 03/31/26
    from
    $ 458
    Viewed: 5 hours ago
    Roundtrip
    Economy

  • Seattle (SEA)to

    Panama City (PTY)
    03/03/26 - 03/17/26
    from
    $ 421
    Viewed: 2 hours ago
    Roundtrip
    Economy

    Atlanta (ATL)to

    Panama City (PTY)
    02/22/26 - 02/27/26
    from
    $ 480
    Viewed: 1 day ago
    Roundtrip
    Economy

    Nashville (BNA)to

    Panama City (PTY)
    03/18/26 - 04/01/26
    from
    $ 462
    Viewed: 5 hours ago
    Roundtrip
    Economy

    Raleigh (RDU)to

    Panama City (PTY)
    03/16/26 - 03/30/26
    from
    $ 472
    Viewed: 20 hours ago
    Roundtrip
    Economy

  • Orlando (MCO)to

    Panama City (PTY)
    03/10/26 - 03/17/26
    from
    $ 574
    Viewed: 3 hours ago
    Roundtrip
    Economy

    Las Vegas (LAS)to

    Panama City (PTY)
    03/18/26 - 04/01/26
    from
    $ 626
    Viewed: 3 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    02/28/26 - 03/04/26
    from
    $ 464
    Viewed: 3 hours ago
    Roundtrip
    Economy

    Washington, D.C. (DCA)to

    Panama City (PTY)
    03/15/26 - 03/19/26
    from
    $ 489
    Viewed: 19 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Houston (IAH)to

Panama City (PTY)
05/07/26 - 05/14/26

Roundtrip

Business

from
$ 1,588
Viewed: 1 day ago

Newark/New York (EWR)to

Panama City (PTY)
05/17/26 - 05/27/26

Roundtrip

Business

from
$ 1,324
Viewed: 17 hours ago

San Francisco (SFO)to

Panama City (PTY)
04/01/26 - 04/08/26

Roundtrip

Business

from
$ 1,474
Viewed: 6 hours ago

Denver (DEN)to

Panama City (PTY)
03/10/26 - 03/19/26

Roundtrip

Business

from
$ 919
Viewed: 1 day ago

Los Angeles (LAX)to

Panama City (PTY)
03/31/26 - 04/08/26

Roundtrip

Business

from
$ 1,026
Viewed: 6 hours ago

Chicago (ORD)to

Panama City (PTY)
04/15/26 - 04/25/26

Roundtrip

Business

from
$ 940
Viewed: 1 day ago

San Antonio (SAT)to

Panama City (PTY)
03/28/26 - 04/06/26

Roundtrip

Business

from
$ 983
Viewed: 1 day ago

Washington, D.C. (IAD)to

Panama City (PTY)
03/17/26 - 03/19/26

Roundtrip

Business

from
$ 972
Viewed: 1 day ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama