Flights from United States to Panama from $ 364*

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Best prices for United flights from United States to Panama

$
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  • Chicago (ORD)to

    Panama City (PTY)
    01/25/26 - 01/29/26
    from
    $ 641
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Denver (DEN)to

    Panama City (PTY)
    01/25/26 - 02/08/26
    from
    $ 589
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Los Angeles (LAX)to

    Panama City (PTY)
    01/23/26 - 02/06/26
    from
    $ 678
    Viewed: 15 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    01/22/26 - 01/26/26
    from
    $ 636
    Viewed: 15 hours ago
    Roundtrip
    Economy

  • Washington, D.C. (IAD)to

    Panama City (PTY)
    01/25/26 - 01/29/26
    from
    $ 522
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Colorado Springs (COS)to

    Panama City (PTY)
    01/22/26 - 01/29/26
    from
    $ 604
    Viewed: 17 hours ago
    Roundtrip
    Economy

    San Diego (SAN)to

    Panama City (PTY)
    01/22/26 - 01/29/26
    from
    $ 694
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    01/24/26 - 01/28/26
    from
    $ 483
    Viewed: 17 hours ago
    Roundtrip
    Economy

  • Salt Lake City (SLC)to

    Panama City (PTY)
    01/19/26 - 02/02/26
    from
    $ 724
    Viewed: 14 hours ago
    Roundtrip
    Economy

    New Orleans (MSY)to

    Panama City (PTY)
    01/22/26 - 01/29/26
    from
    $ 392
    Viewed: 15 hours ago
    Roundtrip
    Economy

    Sacramento (SMF)to

    Panama City (PTY)
    01/22/26 - 01/29/26
    from
    $ 690
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    01/23/26 - 01/27/26
    from
    $ 769
    Viewed: 15 hours ago
    Roundtrip
    Economy

  • San Antonio (SAT)to

    Panama City (PTY)
    01/22/26 - 02/05/26
    from
    $ 540
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Fort Lauderdale (FLL)to

    Panama City (PTY)
    01/25/26 - 02/01/26
    from
    $ 424
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Atlanta (ATL)to

    Panama City (PTY)
    01/23/26 - 02/06/26
    from
    $ 444
    Viewed: 17 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    01/22/26 - 02/05/26
    from
    $ 660
    Viewed: 14 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
04/18/26 - 04/25/26

Roundtrip

Business

from
$ 1,365
Viewed: 12 hours ago

Houston (IAH)to

Panama City (PTY)
02/16/26 - 02/23/26

Roundtrip

Business

from
$ 1,557
Viewed: 14 hours ago

San Francisco (SFO)to

Panama City (PTY)
01/02/26 - 01/08/26

Roundtrip

Business

from
$ 1,688
Viewed: 15 minutes ago

Chicago (ORD)to

Panama City (PTY)
05/30/26 - 06/03/26

Roundtrip

Business

from
$ 928
Viewed: 3 hours ago

Denver (DEN)to

Panama City (PTY)
01/23/26 - 01/25/26

Roundtrip

Business

from
$ 967
Viewed: 16 hours ago

Dallas (DFW)to

Panama City (PTY)
02/23/26 - 03/05/26

Roundtrip

Business

from
$ 850
Viewed: 10 hours ago

Los Angeles (LAX)to

Panama City (PTY)
09/23/26 - 10/05/26

Roundtrip

Business

from
$ 1,205
Viewed: 1 day ago

Phoenix (PHX)to

Panama City (PTY)
01/02/26 - 01/15/26

Roundtrip

Business

from
$ 1,310
Viewed: 21 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama