Flights from United States to Panama from $ 300*

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Best prices for United flights from United States to Panama

$
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  • San Francisco (SFO)to

    Panama City (PTY)
    04/08/26 - 04/15/26
    from
    $ 681
    Viewed: 22 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Panama City (PTY)
    04/09/26 - 04/15/26
    from
    $ 478
    Viewed: 1 day ago
    Roundtrip
    Economy

    Los Angeles (LAX)to

    Panama City (PTY)
    04/07/26 - 04/14/26
    from
    $ 654
    Viewed: 1 day ago
    Roundtrip
    Economy

    Dallas (DFW)to

    Panama City (PTY)
    04/08/26 - 04/22/26
    from
    $ 1,215
    Viewed: 1 hour ago
    Roundtrip
    Economy

  • San Antonio (SAT)to

    Panama City (PTY)
    04/06/26 - 04/20/26
    from
    $ 611
    Viewed: 22 hours ago
    Roundtrip
    Economy

    Seattle (SEA)to

    Panama City (PTY)
    04/08/26 - 04/22/26
    from
    $ 441
    Viewed: 22 hours ago
    Roundtrip
    Economy

    Miami (MIA)to

    Panama City (PTY)
    04/07/26 - 04/11/26
    from
    $ 703
    Viewed: 23 hours ago
    Roundtrip
    Economy

    New Orleans (MSY)to

    Panama City (PTY)
    04/09/26 - 04/13/26
    from
    $ 463
    Viewed: 23 hours ago
    Roundtrip
    Economy

  • Phoenix (PHX)to

    Panama City (PTY)
    04/08/26 - 04/15/26
    from
    $ 1,245
    Viewed: 23 hours ago
    Roundtrip
    Economy

    San Diego (SAN)to

    Panama City (PTY)
    04/06/26 - 04/20/26
    from
    $ 697
    Viewed: 23 hours ago
    Roundtrip
    Economy

    Cleveland (CLE)to

    Panama City (PTY)
    04/08/26 - 04/15/26
    from
    $ 621
    Viewed: 1 hour ago
    Roundtrip
    Economy

    Washington, D.C. (IAD)to

    Panama City (PTY)
    04/09/26 - 04/16/26
    from
    $ 569
    Viewed: 14 minutes ago
    Roundtrip
    Economy

  • Orlando (MCO)to

    Panama City (PTY)
    04/09/26 - 04/16/26
    from
    $ 431
    Viewed: 23 hours ago
    Roundtrip
    Economy

    Boston (BOS)to

    Panama City (PTY)
    04/08/26 - 04/22/26
    from
    $ 677
    Viewed: 1 hour ago
    Roundtrip
    Economy

    Cincinnati (CVG)to

    Panama City (PTY)
    04/09/26 - 04/23/26
    from
    $ 441
    Viewed: 18 hours ago
    Roundtrip
    Economy

    Washington, D.C. (DCA)to

    Panama City (PTY)
    04/09/26 - 04/13/26
    from
    $ 569
    Viewed: 14 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to Panama

$

Newark/New York (EWR)to

Panama City (PTY)
05/22/26 - 05/29/26

Roundtrip

Business

from
$ 1,337
Viewed: 1 day ago

Houston (IAH)to

Panama City (PTY)
05/13/26 - 05/20/26

Roundtrip

Business

from
$ 1,628
Viewed: 11 hours ago

Denver (DEN)to

Panama City (PTY)
05/15/26 - 05/23/26

Roundtrip

Business

from
$ 932
Viewed: 5 hours ago

Chicago (ORD)to

Panama City (PTY)
05/28/26 - 06/04/26

Roundtrip

Business

from
$ 1,065
Viewed: 17 hours ago

San Francisco (SFO)to

Panama City (PTY)
04/10/26 - 04/16/26

Roundtrip

Business

from
$ 1,558
Viewed: 11 hours ago

Austin (AUS)to

Panama City (PTY)
03/30/26 - 04/08/26

Roundtrip

Business

from
$ 944
Viewed: 11 hours ago

Los Angeles (LAX)to

Panama City (PTY)
05/08/26 - 05/10/26

Roundtrip

Business

from
$ 1,081
Viewed: 3 hours ago

Dallas (DFW)to

Panama City (PTY)
05/18/26 - 06/01/26

Roundtrip

Business

from
$ 1,435
Viewed: 17 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to Panama