Flights from United States to the Cayman Islands from $ 280*

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Best prices for United flights from United States to Cayman Islands

$
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  • Denver (DEN)to

    Grand Cayman (GCM)
    01/26/26 - 01/30/26
    from
    $ 360
    Viewed: 16 hours ago
    Roundtrip
    Economy

    Austin (AUS)to

    Grand Cayman (GCM)
    01/05/26 - 01/09/26
    from
    $ 300
    Viewed: 17 hours ago
    Roundtrip
    Economy

    San Francisco (SFO)to

    Grand Cayman (GCM)
    01/19/26 - 02/02/26
    from
    $ 532
    Viewed: 14 hours ago
    Roundtrip
    Economy

    Phoenix (PHX)to

    Grand Cayman (GCM)
    01/18/26 - 01/22/26
    from
    $ 596
    Viewed: 15 hours ago
    Roundtrip
    Economy

  • Los Angeles (LAX)to

    Grand Cayman (GCM)
    01/21/26 - 02/04/26
    from
    $ 346
    Viewed: 15 hours ago
    Roundtrip
    Economy

    Honolulu (HNL)to

    Grand Cayman (GCM)
    01/23/26 - 01/27/26
    from
    $ 1,019
    Viewed: 12 hours ago
    Roundtrip
    Economy

    Las Vegas (LAS)to

    Grand Cayman (GCM)
    01/22/26 - 02/05/26
    from
    $ 562
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Portland, OR (PDX)to

    Grand Cayman (GCM)
    01/22/26 - 01/26/26
    from
    $ 666
    Viewed: 15 hours ago
    Roundtrip
    Economy

  • Omaha (OMA)to

    Grand Cayman (GCM)
    01/25/26 - 01/29/26
    from
    $ 412
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Pittsburgh (PIT)to

    Grand Cayman (GCM)
    01/22/26 - 01/26/26
    from
    $ 296
    Viewed: 10 hours ago
    Roundtrip
    Economy

    Cleveland (CLE)to

    Grand Cayman (GCM)
    01/18/26 - 01/22/26
    from
    $ 480
    Viewed: 17 hours ago
    Roundtrip
    Economy

    Nashville (BNA)to

    Grand Cayman (GCM)
    01/19/26 - 01/23/26
    from
    $ 450
    Viewed: 11 hours ago
    Roundtrip
    Economy

  • Boston (BOS)to

    Grand Cayman (GCM)
    01/17/26 - 01/31/26
    from
    $ 300
    Viewed: 17 hours ago
    Roundtrip
    Economy

    Columbus (CMH)to

    Grand Cayman (GCM)
    01/16/26 - 01/30/26
    from
    $ 360
    Viewed: 12 hours ago
    Roundtrip
    Economy

    Milwaukee (MKE)to

    Grand Cayman (GCM)
    01/19/26 - 02/02/26
    from
    $ 412
    Viewed: 11 hours ago
    Roundtrip
    Economy

    Baltimore (BWI)to

    Grand Cayman (GCM)
    01/20/26 - 01/24/26
    from
    $ 310
    Viewed: 12 hours ago
    Roundtrip
    Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Best business class fares from United States to the Cayman Islands

$

Newark/New York (EWR)to

Grand Cayman (GCM)
01/23/26 - 01/26/26

Roundtrip

Business

from
$ 1,068
Viewed: 1 day ago

Houston (IAH)to

Grand Cayman (GCM)
07/04/26 - 07/04/26

Roundtrip

Business

from
$ 1,050
Viewed: 1 hour ago

Washington, D.C. (IAD)to

Grand Cayman (GCM)
02/28/26 - 03/07/26

Roundtrip

Business

from
$ 906
Viewed: 13 hours ago

Chicago (ORD)to

Grand Cayman (GCM)
02/15/26 - 02/19/26

Roundtrip

Business

from
$ 988
Viewed: 12 hours ago

Denver (DEN)to

Grand Cayman (GCM)
01/21/26 - 02/02/26

Roundtrip

Business

from
$ 984
Viewed: 7 hours ago

Austin (AUS)to

Grand Cayman (GCM)
02/20/26 - 02/24/26

Roundtrip

Business

from
$ 1,512
Viewed: 15 hours ago

San Francisco (SFO)to

Grand Cayman (GCM)
01/17/26 - 01/24/26

Roundtrip

Business

from
$ 1,216
Viewed: 10 hours ago

Phoenix (PHX)to

Grand Cayman (GCM)
02/05/26 - 02/10/26

Roundtrip

Business

from
$ 2,027
Viewed: 6 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Explore more United flights from United States to the Cayman Islands