Flights to Santo Domingo from $ 378*

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United's most popular flights to Santo Domingo (SDQ)

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Newark/New York (EWR)to

Santo Domingo (SDQ)
08/25/26 - 09/24/26
from
$ 403
Viewed: 23 hours ago
Roundtrip
Economy

Houston (IAH)to

Santo Domingo (SDQ)
06/02/26 - 06/09/26
from
$ 638
Viewed: 11 hours ago
Roundtrip
Economy

Fort Lauderdale (FLL)to

Santo Domingo (SDQ)
05/31/26 - 06/07/26
from
$ 395
Viewed: 11 hours ago
Roundtrip
Economy

Philadelphia (PHL)to

Santo Domingo (SDQ)
06/01/26 - 06/05/26
from
$ 635
Viewed: 6 hours ago
Roundtrip
Economy

Chicago (ORD)to

Santo Domingo (SDQ)
06/02/26 - 06/09/26
from
$ 590
Viewed: 10 hours ago
Roundtrip
Economy

Orlando (MCO)to

Santo Domingo (SDQ)
06/05/26 - 06/09/26
from
$ 405
Viewed: 10 hours ago
Roundtrip
Economy

Miami (MIA)to

Santo Domingo (SDQ)
06/02/26 - 06/09/26
from
$ 482
Viewed: 10 hours ago
Roundtrip
Economy

Boston (BOS)to

Santo Domingo (SDQ)
05/18/26 - 05/22/26
from
$ 378
Viewed: 12 hours ago
Roundtrip
Economy

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Business class deals on flights to Santo Domingo (SDQ)

$

Newark/New York (EWR)to

Santo Domingo (SDQ)
05/25/26 - 06/05/26

Roundtrip

Business

from
$ 863
Viewed: 22 hours ago

Houston (IAH)to

Santo Domingo (SDQ)
05/17/26 - 05/26/26

Roundtrip

Business

from
$ 1,110
Viewed: 1 day ago

Fort Lauderdale (FLL)to

Santo Domingo (SDQ)
05/18/26 - 05/23/26

Roundtrip

Business

from
$ 853
Viewed: 3 hours ago

Philadelphia (PHL)to

Santo Domingo (SDQ)
05/08/26 - 05/11/26

Roundtrip

Business

from
$ 1,067
Viewed: 5 hours ago

Chicago (ORD)to

Santo Domingo (SDQ)
05/11/26 - 05/18/26

Roundtrip

Business

from
$ 1,000
Viewed: 2 hours ago

Orlando (MCO)to

Santo Domingo (SDQ)
09/30/26 - 10/05/26

Roundtrip

Business

from
$ 849
Viewed: 1 day ago

Miami (MIA)to

Santo Domingo (SDQ)
05/08/26 - 05/12/26

Roundtrip

Business

from
$ 1,170
Viewed: 1 day ago

Boston (BOS)to

Santo Domingo (SDQ)
06/02/26 - 06/05/26

Roundtrip

Business

from
$ 658
Viewed: 21 hours ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

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Things to do after your flight to Santo Domingo (SDQ)

The capital city of the Dominican Republic, Santo Domingo combines politics with a historic city center that is a UNESCO World Heritage Site — an area that’s sure to charm you.

Santo Domingo’s top attractions

  • Stroll around the Colonial Zone, and see important sites such as the Fortress of Santo Domingo, Cathedral of Santa María la Menor, Panteon Nacional and various churches.
  • Explore different ecosystems within Jardín Botánico Nacional (National Botanical Garden).
  • Tour the museums of Plaza de la Cultura.
  • Walk along the oceanfront promenade, Malecón, and enjoy lovely views and carriage rides.
  • Tour Los Tres Ojos (“the three eyes”), a series of freshwater lagoons and limestone caves.

Best time to travel to Santo Domingo

Both summer and winter are peak times to visit Santo Domingo. Spring and fall offer pleasant weather with fewer crowds. The springtime Carnaval República Dominicana is a great way to experience the lively culture, with parades, competitions, food, music, costumes and masks. The summertime Festival del Merengue features free concerts, dancing in the streets and shows with professional dancers.