Flights to Knoxville from $ 139*
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1 Passenger, Economy
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today
today
United's most popular flights to Knoxville (TYS)
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$
Chicago (ORD)to
Knoxville (TYS)02/11/26 - 02/14/26
from
$ 189
Viewed: 15 hours ago
Roundtrip
Economy
Houston (IAH)to
Knoxville (TYS)03/02/26 - 03/09/26
from
$ 209
Viewed: 16 hours ago
Roundtrip
Economy
Denver (DEN)to
Knoxville (TYS)01/14/26 - 01/17/26
from
$ 229
Viewed: 18 hours ago
Roundtrip
Economy
Washington, D.C. (IAD)to
Knoxville (TYS)02/04/26 - 02/11/26
from
$ 139
Viewed: 13 hours ago
Roundtrip
Economy
Newark/New York (EWR)to
Knoxville (TYS)03/03/26 - 03/10/26
from
$ 262
Viewed: 17 hours ago
Roundtrip
Economy
San Francisco (SFO)to
Knoxville (TYS)02/07/26 - 02/11/26
from
$ 245
Viewed: 14 hours ago
Roundtrip
Economy
Austin (AUS)to
Knoxville (TYS)02/03/26 - 02/07/26
from
$ 195
Viewed: 19 hours ago
Roundtrip
Economy
Orange County (SNA)to
Knoxville (TYS)02/03/26 - 02/10/26
from
$ 243
Viewed: 13 hours ago
Roundtrip
Economy
*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.
Business class deals on flights to Knoxville (TYS)
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flight_land
$
Chicago (ORD)to
Knoxville (TYS)
01/14/26 - 01/19/26
Roundtrip
Business
from
$ 379
Viewed: 1 day ago
Houston (IAH)to
Knoxville (TYS)
01/08/26 - 01/11/26
Roundtrip
Business
from
$ 667
Viewed: 8 hours ago
Denver (DEN)to
Knoxville (TYS)
12/31/25 - 01/07/26
Roundtrip
Business
from
$ 619
Viewed: 3 hours ago
Washington, D.C. (IAD)to
Knoxville (TYS)
12/28/25 - 01/01/26
Roundtrip
Business
from
$ 1,148
Viewed: 4 hours ago
Newark/New York (EWR)to
Knoxville (TYS)
05/12/26 - 05/19/26
Roundtrip
Business
from
$ 538
Viewed: 2 hours ago
San Francisco (SFO)to
Knoxville (TYS)
01/06/26 - 01/08/26
Roundtrip
Business
from
$ 1,040
Viewed: 1 day ago
Austin (AUS)to
Knoxville (TYS)
12/16/25 - 12/19/25
Roundtrip
Business
from
$ 788
Viewed: 1 day ago
Orange County (SNA)to
Knoxville (TYS)
01/07/26 - 01/07/26
Roundtrip
Business
from
$ 1,603
Viewed: 7 hours ago
*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.
Things to do after your flight to Knoxville (TYS)
Fly to Knoxville, Tennessee, from over 200 airports within the United States and an additional 100 airports internationally.
Knoxville’s top attractions
- Explore Great Smoky Mountains National Park, the most visited national park in the U.S.
- Walk through the University of Tennessee Gardens, with over 1,000 wooded plants and 2,000 herbaceous plants.
- Stroll down Gay Street, offering shops, a movie theater and many restaurants.
- Learn about Native American history and culture at the Museum of East Tennessee History.
Best time to travel to Knoxville
Many events have a musical theme, such as the critically acclaimed Big Ears Festival at the end of winter, combining musical performances, workshops and film screenings. Another popular event is the Rhythm N' Blooms Festival in spring, featuring the Great Smoky Mountains as a backdrop. Events such as the springtime Turkish Food Festival and summertime Knox Asian Festival pay tribute to local diversity.