Flights from Panama starting at $ 381*

Promotion Code

United business class fares from Panama

$

Panama City (PTY)to

Newark/New York (EWR)
01/05/2026 - 10/05/2026

Roundtrip

Business

from
$ 1,497
Viewed: 23 hours ago

Panama City (PTY)to

Tel Aviv (TLV)
31/03/2026 - 15/04/2026

Roundtrip

Business

from
$ 5,098
Viewed: 23 hours ago

Panama City (PTY)to

Houston (IAH)
29/01/2026 - 20/02/2026

Roundtrip

Business

from
$ 1,737
Viewed: 14 hours ago

Panama City (PTY)to

San Francisco (SFO)
20/04/2026 - 10/05/2026

Roundtrip

Business

from
$ 2,664
Viewed: 1 day ago

Panama City (PTY)to

Las Vegas (LAS)
12/02/2026 - 17/02/2026

Roundtrip

Business

from
$ 1,314
Viewed: 15 hours ago

Panama City (PTY)to

Denver (DEN)
08/01/2026 - 16/01/2026

Roundtrip

Business

from
$ 1,907
Viewed: 11 hours ago

Panama City (PTY)to

Los Angeles (LAX)
13/02/2026 - 18/02/2026

Roundtrip

Business

from
$ 1,277
Viewed: 12 hours ago

Panama City (PTY)to

Dallas (DFW)
16/01/2026 - 26/02/2026

Roundtrip

Business

from
$ 1,001
Viewed: 17 minutes ago

*Prices have been available for round trips within the last 48 hours and may not be currently available. For Economy class, fares listed may be Basic Economy, which is our most restrictive fare option and subject to additional restrictions. Additional baggage charges and fees for other optional service may apply. Other terms and conditions may apply. Schedules are subject to change without notice.

Airports tips for your flight from Panama

United offers flights from Panama to over 340 destinations worldwide.

Whether you visit Panama to see the Panama Canal, take part in the Fiestas Patrias or hike the Pipeline Road, travel to your next destination with United. United flights from Panama depart from Tocumen International Airport (PTY) in Panamá City.